Antibiotics used to be a "secret weapon" for humans to fight against many diseases. In the late 19th and early 20th centuries, human life was greatly improved due to the discovery of a series of antibiotics. However, less than a hundred years after the invention, antibiotics have gradually stepped down from the "altar" due to the increasing resistance of bacteria to antibiotics, and even become a major challenge in the future medical and health field.

In December 2015, Chinese scientist Tu Yu, who won the Nobel Prize in Physiology and Medicine, pointed out in her award speech that the resistance of artemisinin has been produced in the Greater Mekong River Basin in Southeast Asia. As early as 2005, cases in western Cambodia confirmed for the first time that malaria was resistant to artemisinin. Although this did not lead to complete failure of artemisinin treatment, it did delay the elimination of Plasmodium falciparum in artemisinin-removing patients. This specific drug for the treatment of malaria is facing the potential danger of failure.

The efficacy of antibiotics is generally declining because bacteria that are resistant to antibiotics are rapidly spreading, and bacteria with resistance are not killed by certain antibiotics, and then they are no longer restricted, and even their resistance is passed on. Give other kinds of bacteria. Hua Jiehong, Minister Counselor of the European Union Delegation to China, said that due to the resistance to antibiotics, some common pathogens are becoming so-called "superbugs". Once antibiotics fail, our lives will be full of dangers – minor bruises can cause death, and mild ear infections can cause deafness.

The problem of antibiotic resistance has become a problem that has plagued countries around the world. The World Health Organization has issued a report saying that by 2050, because bacteria are resistant to antibiotics, 10 million people will die each year, which is equivalent to one person losing their life every three seconds, and the harm will exceed cancer. At the same time, the most worrying thing is that this kind of harm is climbing year by year. For example, E. coli treated with general antibiotics can be effective, but in recent years, many countries have reported that some patients do not use even the most potent antibiotics. At present, about 25,000 people die in Europe every year, causing 1.5 billion euros in medical costs and economic losses every year in the EU. On a global scale, about 700,000 people die every year from various drug-resistant infections, 230,000. The newborn is therefore aborted.

However, the development of new drugs for antibiotic resistance is difficult to keep up with the speed of drug resistance. A report released by the World Health Organization in September 2017 pointed out that the development of new antibiotics is currently seriously inadequate and it is difficult to cope with the growing threat of antibiotic resistance. The report warns that global antibiotics are on the verge of exhaustion. The report believes that the problem of antibiotic resistance has seriously jeopardized the progress of modern medicine. It is urgent to increase investment in research and development of antibiotic resistance infection, otherwise the world will be forced to return to small surgery caused by common infections. The age of death.

WHO emphasizes that pharmaceutical companies and researchers must immediately focus on new antibiotics that can treat certain serious infections that can lead to death within a few days. The repair of existing antibiotic types by most drugs currently in the clinical phase is only a short-term solution. Antibiotic-resistant infections identified by WHO as the greatest health threat, including drug-resistant tuberculosis, which causes approximately 250,000 deaths per year, have few potential effective treatment options. For more than 70 years, only two treatments have been resistant. New antibiotics for tuberculosis enter the market. If you want to end tuberculosis, there is an urgent need to invest more than $800 million annually in research on new anti-tuberculosis drugs.

In addition, the abuse of antibiotics is also an important cause of the accelerated emergence of antibiotic resistance. According to data from a US research institute, global antibiotic consumption increased by 65% between 2000 and 2015. Although antibiotics are a specific treatment for certain diseases, over-reliance on antibiotic treatment can only be counterproductive. Compared with the research and development and investment of new antibiotics, the public should learn to use scientific and cautious antibiotics as soon as possible. Otherwise, we will probably die from an ordinary infection in the future, instead of the cancer, AIDS and other malignant diseases that people fear today.

Perhaps, in the future, we can only help us with some inorganic antibiotics, and nano silver will become the first choice!

According to the information of the science network