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Classification and characteristics of nano silver, silver ions and antibacterial agents
Edit:Shangmeng Technology Wuxi Co., Ltd.   UpDate:2019-01-22

(1) Pharmacy. There are powders and solutions. Appeared earlier. In the modern pharmacopoeia, it has successively contained four silver-containing drugs, such as silver nitrate, protein silver, silver charcoal, silver sulfadiazine, for the treatment of conjunctivitis, gonorrhea, cystitis, dysentery, enteritis, burns and other diseases. . The representative product is silver nitrate eye drops. The most used is silver nitrate. Medically, 1% concentration of silver nitrate is commonly used in neonatal eye drops for gonococcal infection and for the treatment of conjunctivitis.
(2) Electrolytic silver ions. liquid. It appeared early, but it was difficult to industrialize for a long time. High concentration, high purity manufacturing is a recent breakthrough.
(3) Nano silver . Or silver. powder. There are a variety of carrier materials available for use in the manufacturing process, so there are many products on the market. The manufacturing process of nano silver requires a mineral such as zirconium phosphate, apatite or zeolite as a carrier, wherein the silver content is about 3%. In principle, by processing the silver-containing carrier into nano-scale micropowder and increasing the unit surface area of silver, the release amount of silver ions is increased, and the bactericidal power is improved. The main use of nano-silver micropowder is to process antibacterial fiber. If the nano-silver powder is to be processed into an aqueous solution, the processing method is to dissolve the micropowder in water. Therefore, the nanosilver solution is a solution containing a carrier, and the concentration of the nanosilver solution is the concentration of silver ions of the mineral-containing carrier.
Nanosilver is actually a general term for products that contain a variety of manufacturing methods, different carriers, and varying quality effects. Nano units can be called nanometers from 1 to 999 nanometers, each phase is 1 nanometer unit, and the difference in surface area will increase geometrically. It is conceivable that the difference in surface area between a 1 nanometer unit and a 999 nanometer unit would be enormous. The smaller the nano unit, the larger the surface area, and the more free silver ions, the better the sterilization effect. Therefore, the same is the nano silver, the quality price is very different. At present, the nanometer unit of the highest level of nano silver products (Japan East Asia Synthetic Co., Ltd.) is 4 nanometer units. Generally, nano silver products are in the range of 20 to 30 nanometers. The products are mixed, and the price gap can be imagined. Coupled with the fact that nanometers are difficult to verify, it is difficult to judge even with sophisticated instruments. This has affected the credit of nano silver. Therefore, it is also called silver (nano silver). In the market, some 1 kilograms sell for several thousand yuan, and some are only a few hundred yuan. The difference is ten times, and it is difficult for customers to adapt.
The above three types of silver ion antibacterial agents, the components that achieve their bactericidal function are all containing silver ions.


Different types of silver ion antibacterial agents are limited in their use due to their physical form, performance and composition. A silver-based antibacterial agent represented by silver nitrate, although appeared earlier. However, there is a nitric acid component, so the use is mainly limited to eye drops. In developed countries such as Europe, America and Japan, it is not allowed to be used in skin and mucous membranes and environmental sterilization. The use of antibacterial agents such as silver nitrate is professional, and nano silver and electrolytic silver are widely used and are relatively easy to be confused. Nano silver solution and electrolytic silver ion solution are the same and different concepts. This is something to be pointed out. The bactericidal functional ingredients contained are all silver ions. But the content is different. The electrolytic silver solution contains pure silver ions, and the carrier contained in the nano silver solution is the main component, and the silver ions are only a small amount. Second, the concentration measurement units used for nano silver and electrolytic silver are both ml/g (ppm), and the concentration of the pure silver ion contained in the electrolytic silver solution that is commonly used internationally is indicated. The labeled concentration of nanosilver is the concentration comprising the nanocarrier. Moreover, due to the uneven technology of nano silver manufacturers, even if the same concentration is indicated, the actual concentration of silver ions is not the same, and the sterilization effect is naturally different.
From the above, it is difficult to compare the concentration of the electrolytic silver ion solution with the nano silver ion solution. We can only make a rough analysis and comparison with the minimum inhibitory concentration. The nano silver solution 250 to 500 ppm corresponds to a pure silver ion concentration of 1 ppm. That is, the bacteriostatic force of the electrolytic silver ion solution at 1 ppm is approximately equivalent to the bacteriostatic force of the nano silver solution at a concentration of 250 to 500 ppm. which is:
The nano silver ion solution [MIC] is: 62 ppm to 250 ppm The electrolytic silver ion solution [MIC] is: 0.05 ppm to 0.5 ppm. The simple concentration comparison is about 500 to 1.

The electrolytic silver ionic liquid is a colorless, odorless transparent liquid.
The nanosilver solution is divided into two types, colorless, transparent, and brown, depending on the carrier. The brown solution uses inexpensive materials such as apatite and is inexpensive.

The physical form of nanosilver is a powder. Many solutions using nanosilver powders to replace silver ions are now on the market. The speed and concentration of silver ions eluted (released) from the carrier are different depending on the nano silver powder of each manufacturer, and the process is cumbersome and the price is high. Therefore, processing silver ion liquid from nano silver is not the advantage of silver loading.
The electrolytic silver ion product is a liquid. It is a colorless, odorless, non-toxic transparent aqueous solution containing no carrier particles. Therefore, it can be used for mucosal tissues such as eyes, mouth, nostrils, skin and vagina. Theoretically, as long as silver ions do not react with other elements, do not form silver compounds, and do not become new substances, the bactericidal effect of silver ions has always existed. Even if silver ions enter the nucleus of the bacteria, causing the bacteria to die and then dissolving again, they can still be sterilized.

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